Psoriasis Treatment: A Pharmacogenetics Breakthrough

Psoriasis Treatment: A Pharmacogenetics Breakthrough

BioCertica Content Team

Psoriasis, a chronic autoimmune skin condition characterized by red, flaky, crusty patches of skin covered with silvery scales, affects millions globally. While there's no cure, treatment focuses on controlling symptoms and preventing flare-ups. This article delves into how pharmacogenetics transforms psoriasis treatment, offering a personalized approach to managing this complex condition.

Challenges in Psoriasis Treatment

Traditional treatments range from topical creams and phototherapy to systemic medications and biologics. However, patient responses vary due to the disease's heterogeneity and individual genetic differences, often leading to a trial-and-error approach in treatment selection.

The Promise of Personalized Medicine in Psoriasis

Personalized medicine, tailoring treatment plans to the individual's genetic makeup, lifestyle, and health history, holds promise in improving psoriasis management. It aims to identify the most effective and safest treatment options for each patient, enhancing their quality of life.

The Role of Pharmacogenetics in Psoriasis Therapy

Pharmacogenetics studies how genetic variations affect an individual's response to drugs. Pharmacogenetic testing can predict how a patient might react to certain medications, including traditional systemic drugs and newer biologics, in psoriasis, enabling more precise and effective treatment plans.

Implementing Pharmacogenetics in Clinical Practice

Incorporating pharmacogenetics into treatment involves genetic testing to guide therapeutic decisions. This approach has been shown to reduce adverse drug reactions, improve treatment efficacy, and decrease healthcare costs by minimizing ineffective treatments.

BioCertica's Contribution to Personalized Psoriasis Treatment

BioCertica offers a pharmacogenetics report that analyzes genetic markers associated with drug metabolism and response in psoriasis patients. This report provides valuable insights, helping healthcare providers to customize treatment strategies that are more likely to succeed.


Integrating pharmacogenetics into treatment is a significant step towards personalized medicine. By leveraging genetic insights, healthcare providers can offer tailored therapies, improving patient outcomes and paving the way for more innovative and effective psoriasis management strategies.


1. Muñoz-Aceituno, E., Martos-Cabrera, L., Ovejero-Benito, M. C., Reolid, A., Abad-Santos, F., & Daudén, E. (2020). Pharmacogenetics update on biologic therapy in psoriasis. Medicina56(12), 719.

2. Berna-Rico, E., Perez-Bootello, J., Abbad-Jaime de Aragon, C., & Gonzalez-Cantero, A. (2023). Genetic Influence on Treatment Response in Psoriasis: New Insights into Personalized Medicine. International Journal of Molecular Sciences24(12), 9850.

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