DNA Cardiovascular & Traits
DNA Cardiovascular & Traits
Take care of your heart this September as we celebrate World Heart Day. Get your cardiovascular and traits DNA test for 50% off.
Cardiovascular DNA Test
Knowing your genetic risk can help you take good care of your heart when it comes to your cardiovascular health. The following is covered in this test:
- Risk for atrial fibrillation (a heart condition characterized by irregular and rapid heart rate)
- Caffeine metabolite levels
- HDL ("good") cholesterol levels
- LDL ("bad") cholesterol levels
- Triglycerides levels
- Risk for a heart attack
- Ability to manage blood triglycerides (omega-3)
- Risk for PAD (peripheral arterial disease)
- Risk for venous thrombosis
Traits DNA Test
Genetics is mainly about inheriting traits from your parents. Your height, weight, hair, and eye color depend on your genetics. However, you do not inherit only physically visible traits. Your behavior, intelligence, memory, and even more depending on your genetics.
This fun and exciting genetic test might teach you something new about yourself and your genetics. In this test, you would find your earwax type, coffee consumption, intelligence, memory, aggression, and many more.
The following is covered in this test:
- Earwax type and body odor
- Intelligence (non-verbal)
- Baldness (males only)
- Long term memory
- Working memory
- Pair bonding and sociability
- Likelihood of having thin and wavy hair
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What can I expect from the DNA Cardiovascular & Traits kit?
Included in my results
The science behind it
BioCertica provides genetic reports for 75 traits for which it assesses the genetic predisposition based on peer-reviewed scientific studies. These 75 traits are distributed across multiple topic-based packages, but you can read more about this in previous sections.
The critical question we want to answer here is how we estimate the genetic predisposition for those 75 traits. We are proud to inform you that we are the first African-based direct-to-consumer genetic testing company to estimate genetic predisposition to various traits and diseases using the polygenic risk scoring methodology.
We will tell you more about the polygenic risk scoring methodology in a bit. Before that, to underline that most of today’s genetic risk scoring reporting is based on individual genetic variants that are found to be associated with a given trait. For example, let’s say a genetic variant associated with whether you can detect bitter taste or not or similar traits controlled by single genetic variants.
The problem starts once you want to assess the genetic risk for so-called complex traits and diseases such as for example the genetic risk for heart attack. You might ask why. The problem with complex diseases is that those are not determined by one single gene but by dozens, hundreds, and even thousands of genetic variants, and not all of those genetic variants have equal contributions. In those cases, how do we estimate the risk for that kind of disease?
Well, to handle those complex traits, we at BioCertica, as already mentioned, implemented the polygenic risk score methodology. Polygenic risk scoring methodology leverages the wealth of scientific knowledge accumulated through hundreds of genome-wide association studies (GWAS). Thousands of individuals were tested in GWAS to identify genetic variants associated with any disease or trait. These studies are the bedrock for building polygenic risk scores for any trait. Important to note that here we talk about peer-reviewed studies published in the leading scientific journals.
For our purposes, we leverage two primary databases: the PGS Catalog and GWAS Catalog, that contain information about traits, studies, and genetic variants based on which we at BioCertica build our products. These databases are managed by leading scientific institutions such as European Molecular Biology Laboratory and European Bioinformatics Institute. In addition, traits and studies reported in these databases pass an additional layer of peer-reviewed process. This is the reason why we use these databases as the primary source for building our new products.
However, in order to leverage the potential of PGS and GWAS Catalogs, we at BioCertica had to develop a series of tools to enrich our originally produced genotype data from our users. This means that we implemented an in-house genotype imputation procedure to sufficiently enrich our users' genotype data to leverage the potential of the polygenic risk score methodology.
‘Wow! I am absolutely floored by the detailed representation of ME!’
Tamaryn Leigh Buchner - Another satisfied customer
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We work with nationwide delivery partners and your kit is usually shipped the same day.
Our commitmentRead more
For every box returned, we'll donate 1kg of maize meal to our a family in need.
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